OR2G6

Protein-coding gene in the species Homo sapiens
OR2G6
Identifiers
AliasesOR2G6, olfactory receptor family 2 subfamily G member 6
External IDsMGI: 3031217; HomoloGene: 105344; GeneCards: OR2G6; OMA:OR2G6 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for OR2G6
Genomic location for OR2G6
Band1q44Start248,508,073 bp[1]
End248,527,337 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for OR2G6
Genomic location for OR2G6
Band11|11 B1.2Start49,410,475 bp[2]
End49,418,026 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • prostate

  • human kidney
Top expressed in
  • morula

  • adrenal gland

  • islet of Langerhans

  • white adipose tissue

  • duodenum
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

391211

404337

Ensembl

ENSG00000188558

ENSMUSG00000107417

UniProt

Q5TZ20

Q7TQT2

RefSeq (mRNA)

NM_001013355

NM_207574

RefSeq (protein)

NP_001013373

NP_997457

Location (UCSC)Chr 1: 248.51 – 248.53 MbChr 11: 49.41 – 49.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2G6 is a protein that in humans is encoded by the OR2G6 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188558 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000107417 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR2G6 olfactory receptor, family 2, subfamily G, member 6".

Further reading

  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

  • v
  • t
  • e
Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13
Stub icon

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e
Stub icon

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e