OR1Q1

Protein-coding gene in the species Homo sapiens
OR1Q1
Identifiers
AliasesOR1Q1, HSTPCR106, OR1Q2, OR1Q3, OR9-25, OR9-A, OST226, OST226OR9-A, TPCR106, olfactory receptor family 1 subfamily Q member 1
External IDsMGI: 3030191; HomoloGene: 17320; GeneCards: OR1Q1; OMA:OR1Q1 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for OR1Q1
Genomic location for OR1Q1
Band9q33.2Start122,614,738 bp[1]
End122,615,682 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for OR1Q1
Genomic location for OR1Q1
Band2|2 BStart36,883,839 bp[2]
End36,891,859 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • stromal cell of endometrium

  • Achilles tendon

  • urinary bladder

  • gallbladder

  • myometrium

  • fundus

  • prefrontal cortex

  • sigmoid colon

  • body of stomach
Top expressed in
  • spermatid
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • signal transducer activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

158131

258616

Ensembl

ENSG00000165202

ENSMUSG00000055838

UniProt

Q15612

Q8VFP4

RefSeq (mRNA)

NM_012364

NM_146623

RefSeq (protein)

NP_036496

NP_666834

Location (UCSC)Chr 9: 122.61 – 122.62 MbChr 2: 36.88 – 36.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 1Q1 is a protein that in humans is encoded by the OR1Q1 gene.[5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165202 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055838 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR1Q1 olfactory receptor, family 1, subfamily Q, member 1".

Further reading

  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (February 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
  • Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (September 2002). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
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Family 4
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Family 8
Family 9
Family 10
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Family 13
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