Protein-coding gene in the species Homo sapiens
| OR1K1 |
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| Identifiers |
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| Aliases | OR1K1, hg99, olfactory receptor family 1 subfamily K member 1 |
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| External IDs | HomoloGene: 124591; GeneCards: OR1K1; OMA:OR1K1 - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 9 (human)[1] |
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| | Band | 9q33.2 | Start | 122,800,123 bp[1] |
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| End | 122,801,073 bp[1] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - stromal cell of endometrium
- gonad
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| | | More reference expression data |
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| BioGPS |  | | More reference expression data |
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| Gene ontology |
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| Molecular function | - G protein-coupled receptor activity
- olfactory receptor activity
- transmembrane signaling receptor activity
- signal transducer activity
| | Cellular component | - integral component of membrane
- plasma membrane
- membrane
| | Biological process | - sensory perception of smell
- detection of chemical stimulus involved in sensory perception of smell
- detection of chemical stimulus involved in sensory perception
- signal transduction
- response to stimulus
- G protein-coupled receptor signaling pathway
| | Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 9: 122.8 – 122.8 Mb | n/a |
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| PubMed search | [2] | n/a |
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| Wikidata |
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Olfactory receptor 1K1 is a protein that in humans is encoded by the OR1K1 gene.[3]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000165204 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: OR1K1 olfactory receptor, family 1, subfamily K, member 1". Ncbi.nlm.nih.gov. Retrieved 2013-10-24.
Further reading
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
