ARNT |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/8/83/Protein_ARNT_PDB_1x0o.png/250px-Protein_ARNT_PDB_1x0o.png) |
Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 4PKY, 1X0O, 2A24, 2B02, 2HV1, 2K7S, 3F1N, 3F1O, 3F1P, 3H7W, 3H82, 4EQ1, 4GHI, 4GS9, 4H6J, 4LPZ, 4XT2 | | |
Ідентифікатори |
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Символи | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2, aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor nuclear translocator |
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Зовнішні ІД | OMIM: 126110 MGI: 88071 HomoloGene: 1261 GeneCards: ARNT |
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Онтологія гена |
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Молекулярна функція | • sequence-specific DNA binding • DNA binding • protein dimerization activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001105 transcription coactivator activity • aryl hydrocarbon receptor binding • transcription factor binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • protein homodimerization activity • sequence-specific double-stranded DNA binding • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity |
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Клітинна компонента | • цитоплазма • transcription regulator complex • нуклеоплазма • RNA polymerase II transcription regulator complex • клітинне ядро • ядерні тільця |
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Біологічний процес | • positive regulation of vascular endothelial growth factor receptor signaling pathway • диференціація клітин • response to hypoxia • GO:0009373 regulation of transcription, DNA-templated • positive regulation of endothelial cell proliferation • regulation of transcription from RNA polymerase II promoter in response to oxidative stress • positive regulation of erythrocyte differentiation • embryonic placenta development • mRNA transcription by RNA polymerase II • positive regulation of protein sumoylation • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • intracellular receptor signaling pathway • regulation of transcription from RNA polymerase II promoter in response to hypoxia • positive regulation of vascular endothelial growth factor production • positive regulation of glycolytic process • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of hormone biosynthetic process • xenobiotic metabolic process |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/PBB_GE_ARNT_218222_x_at_fs.png/250px-PBB_GE_ARNT_218222_x_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PBB_GE_ARNT_218221_at_fs.png/250px-PBB_GE_ARNT_218221_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/9/95/PBB_GE_ARNT_210828_s_at_fs.png/250px-PBB_GE_ARNT_210828_s_at_fs.png) |
Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | NM_001197325 NM_001286035 NM_001286036 NM_001668 NM_178426
| NM_178427 NM_001350224 NM_001350225 NM_001350226 |
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RefSeq (білок) | NP_001184254 NP_001272964 NP_001272965 NP_001659 NP_848514
| NP_001337153 NP_001337154 NP_001337155 |
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Локус (UCSC) | Хр. 1: 150.81 – 150.88 Mb | Хр. 3: 95.34 – 95.4 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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