Transition nuclear protein

Proteins that are involved in the packaging of sperm nuclear DNA during spermiogenesis

Transition nuclear proteins (TNPs) are proteins that are involved in the packaging of sperm nuclear DNA during spermiogenesis. They take the place of histones associated with the sperm DNA, and are subsequently themselves replaced by protamines.[1]

TNPs in humans include TNP1 and TNP2.

See also

  • Chromatin
  • Histone
  • Protamine
  • Sperm
  • Spermatogenesis
  • Spermiogenesis

References

  1. ^ Meistrich, ML; Mohapatra, B; Shirley, CR; Zhao, M (May 2003). "Roles of transition nuclear proteins in spermiogenesis". Chromosoma. 111 (8): 483–8. doi:10.1007/s00412-002-0227-z. PMID 12743712. S2CID 28866607.
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Structures of the cell nucleus / nuclear protein
Envelope (membrane)/
nuclear laminaNucleolusOther
SMC protein:
Transition nuclear protein:
  • see also transcription factors and intracellular receptors
see also nucleus diseases
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