RHOXF1

Protein-coding gene in the species Homo sapiens
RHOXF1
Identifiers
AliasesRHOXF1, OTEX, PEPP1, Rhox homeobox family member 1
External IDsOMIM: 300446; HomoloGene: 64643; GeneCards: RHOXF1; OMA:RHOXF1 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for RHOXF1
Genomic location for RHOXF1
BandXq24Start120,109,051 bp[1]
End120,115,913 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • Brodmann area 23

  • adipose tissue

  • hypothalamus

  • left uterine tube

  • Brodmann area 9

  • subcutaneous adipose tissue

  • canal of the cervix

  • abdominal fat

  • amygdala
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • sequence-specific DNA binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding
Cellular component
  • nucleus
Biological process
  • multicellular organism development
  • gamete generation
  • regulation of transcription, DNA-templated
  • intracellular steroid hormone receptor signaling pathway
  • sexual reproduction
  • transcription, DNA-templated
  • positive regulation of gene expression
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

158800

n/a

Ensembl

ENSG00000101883

n/a

UniProt

Q8NHV9

n/a

RefSeq (mRNA)

NM_139282

n/a

RefSeq (protein)

NP_644811

n/a

Location (UCSC)Chr X: 120.11 – 120.12 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Rhox homeobox family member 1 is a protein that in humans is encoded by the RHOXF1 gene.[3][4][5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101883 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Geserick C, Weiss B, Schleuning WD, Haendler B (Aug 2002). "OTEX, an androgen-regulated human member of the paired-like class of homeobox genes". Biochem J. 366 (Pt 1): 367–75. doi:10.1042/BJ20020399. PMC 1222745. PMID 11980563.
  4. ^ Wayne CM, MacLean JA, Cornwall G, Wilkinson MF (Dec 2002). "Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis". Gene. 301 (1–2): 1–11. doi:10.1016/S0378-1119(02)01087-9. PMID 12490318.
  5. ^ "Entrez Gene: OTEX paired-like homeobox protein OTEX".

Further reading

  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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