PNO1

Protein-coding gene in the species Homo sapiens
PNO1
Identifiers
AliasesPNO1, KHRBP1, RRP20, partner of NOB1 homolog
External IDsMGI: 1913499; HomoloGene: 6961; GeneCards: PNO1; OMA:PNO1 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for PNO1
Genomic location for PNO1
Band2p14Start68,157,888 bp[1]
End68,176,238 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for PNO1
Genomic location for PNO1
Band11|11 A2Start17,153,198 bp[2]
End17,161,568 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • buccal mucosa cell

  • tendon of biceps brachii

  • olfactory bulb

  • thoracic diaphragm

  • beta cell

  • internal globus pallidus

  • mucosa of urinary bladder

  • cartilage tissue

  • triceps brachii muscle

  • right ventricle
Top expressed in
  • plantaris muscle

  • epiblast

  • extensor digitorum longus muscle

  • interventricular septum

  • embryo

  • primitive streak

  • cardiac muscle tissue of left ventricle

  • sternocleidomastoid muscle

  • upper arm

  • triceps brachii muscle
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • nucleic acid binding
  • RNA binding
Cellular component
  • nucleus
  • nucleolus
  • cytosol
  • nucleoplasm
Biological process
  • rRNA processing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

56902

66249

Ensembl

ENSG00000115946

ENSMUSG00000020116

UniProt

Q9NRX1

Q9CPS7

RefSeq (mRNA)

NM_001329916
NM_001329917
NM_020143

NM_025443

RefSeq (protein)

NP_001316845
NP_001316846
NP_064528

NP_079719

Location (UCSC)Chr 2: 68.16 – 68.18 MbChr 11: 17.15 – 17.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA-binding protein PNO1 is a protein that in humans is encoded by the PNO1 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115946 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020116 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhou GJ, Zhang Y, Wang J, Guo JH, Ni J, Zhong ZM, Wang LQ, Dang YJ, Dai JF, Yu L (Oct 2004). "Cloning and characterization of a novel human RNA binding protein gene PNO1". DNA Seq. 15 (3): 219–24. doi:10.1080/10425170410001702159. PMID 15497447. S2CID 29787759.
  6. ^ "Entrez Gene: PNO1 partner of NOB1 homolog (S. cerevisiae)".

Further reading

  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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