Clortermine
Chemical compound
- ?
administration
- none
- US: Schedule III
- In general: ℞ (Prescription only)
- 1-(2-chlorophenyl)-2-methylpropan-2-amine
- 10389-73-8 N
- 25223
- DB01527 Y
- 23558 Y
- 4FA88HM3IX
- D03566 Y
- ChEMBL1697833 N
- DTXSID0022850
- Interactive image
- Clc1ccccc1CC(N)(C)C
InChI
- InChI=1S/C10H14ClN/c1-10(2,12)7-8-5-3-4-6-9(8)11/h3-6H,7,12H2,1-2H3 Y
- Key:HXCXASJHZQXCKK-UHFFFAOYSA-N Y
Clortermine (Voranil) was developed by Ciba in the 1960s[1] and is an anorectic drug of the amphetamine class.[2] It is the 2-chloro analogue of the better known appetite suppressant phentermine, and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine,[3] and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent.[citation needed]
See also
- 3,4-Dichloroamphetamine
- Cericlamine
- Chlorphentermine
- Cloforex
- Etolorex
- Methylenedioxyphentermine
- Phentermine
References
- ^ US patent 3415937, "The Suppression of Appetite with 1-(o-Chlorophenyl)-2-Methyl-2-Propylamine"
- ^ Triggle DJ (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall / CRC. ISBN 0-412-46630-9.
- ^ Sannerud CA, Brady JV, Griffiths RR (1989). "Self-injection in baboons of amphetamines and related designer drugs". NIDA Research Monograph. 94: 30–42. PMID 2514366.
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antagonists
glucagon agonists
receptor agonists
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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